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BIOTAGE snap ultra 100 g silica gel column
Snap Ultra 100 G Silica Gel Column, supplied by BIOTAGE, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/snap+ultra+100+g/snap+ultra+silica+gel+column/us12357701-758-18-13
Average 90 stars, based on 1 article reviews
snap ultra 100 g silica gel column - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Purification:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Column Chromatography:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Thin Layer Chromatography:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Nuclear Magnetic Resonance:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Residue:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

High Performance Liquid Chromatography:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Reflux:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Chromatography:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).

Recrystallization:

Article Title: Superelectrophilic Nonclassical Carbocations.
Article Snippet: The product was purified using column chromatography (Biotage SNAP Ultra 100 g, 5-10% ethyl S5 acetate in hexanes) TLC: 10% ethyl acetate in hexanes (Rf: 0.57). mp 54-55 oC.

Article Title: BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
Article Snippet: The residue was purified by column chromatography (Machine: Biotage Isolera; column: Biotage SNAP Ultra 100 g; eluent: Cy/EE: 12% EE → 100% EE; flow: 100 mL/min).

Article Title: On the Ability of the N-O Bond to Support a Stable Stereogenic Axis: Peptide-Catalyzed Atroposelective N -Oxidation.
Article Snippet: HPLC (Chiralpak IA column, 20% EtOH/hexanes, 1.0 mL/min flowrate, 25 °C, 250 nm): minor enantiomer tR = 5.1 min, major enantiomer tR = 6.1 min. N Me Me O N H N O N H S12 2-(3-chloropyridin-2-yl)-3-methyl-N-phenylbenzamide (3f) Using general procedure 3 with 3-chloro-2-(o-tolyl)pyridine (S1f) (0.56 g, 2.8 mmol) and benzoyl azide (S2a) (0.74 g, 5.0 mmol) in a round bottom flask equipped with reflux condenser, the crude product was purified using normal phase column chromatography (Biotage®, SNAP Ultra 100 g, gradient = 0–30% EtOAc/hexanes for 15 CV, the 30% EtOAc/hexanes for 5.7 CV), then reverse phase column chromatography chromatography (Biotage®, SNAP Ultra C18 60 g, gradient = 0–30% MeOH/H2O for 3 CV, then 30–70% MeOH/H2O for 12 CV, then 70–93% MeOH/H2O for 2.2 CV, then 93–100% MeOH/H2O for 0.7 CV, then 100% MeOH for 5.9 CV) to afford a white solid (113 mg, 12% yield).

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 13 CV: 0-25%) yielded S12 as a white foam (1.49 g, 2.31 mmol, 72% over 2 steps).

Article Title: Structural optimization of diblock polymers that undergo thermo-responsive nanoparticle self-assembly for intravitreal drug delivery
Article Snippet: The mixture was passed through flash column (Biotage SNAP ultra 100 g), using gradient eluent dichloromethane (DCM)/methanol with methanol increased from 0 to 10 % (v/ v).

Article Title: Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities.
Article Snippet: Basidiomycetes with a wide variety of skeletons of secondary metabolites can be expected to be the source of new interesting biological compounds.. During our research on basidiomycetes, two new C-29 oxygenated oleanane-type triterpenes (1 and 2) and torulosacid (3), a muurolene type sesquiterpenoid with a five-membered ether ring along with nine known compounds (4–12), were isolated from the MeOH extract of the fruiting bodies of Fuscoporia torulosa.. The structures of 1–3 were determined by NMR and HREIMS analysis.

Article Title: Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism.
Article Snippet: After volatiles were removed in vacuo, the residue was purified by medium-pressure column chromatography (Biotage SNAP Ultra 100 g, hexane: ethyl acetate = 90:10 to 0:100) to afford the title compound ((E)-3-(2-methoxyethyl) 5-(3-(pyridin-4-yl)allyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate) (988 mg, 45% yield) as a yellow solid.

Article Title: An Asymmetric Aromatic Finkelstein Reaction: A Platform for Remote Diarylmethane Desymmetrization.
Article Snippet: Purification by automated column chromatography (Biotage, SNAP Ultra 100 g, gradient EtOAc in hexanes: 10 CV: 0-20%) yielded 10 as an orange foam (815 mg, 1.58 mmol, 27% over 2 steps).



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